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Genetics and Reproduction
12.11.12 Understand Mendel's law of segregation and also that genes do not always separate as hypothesized by Mendel's law of segregation. Understand that if genes are located close to each other on the same chromosome, then they are linked and may undergo independent assortment.
12.11.13 Identify and be able to apply the following concepts: trait, alleles, dominant allele, recessive allele, gametes, genotype, homozygous, heterozygous, chromosome, meiosis, and mitosis.
12.11.14 Answer questions about given Punnett squares.
12.11.15 Understand that meiosis is an early step in sexual reproduction in which the pairs of chromosomes separate and segregate randomly during cell division to produce gametes containing one chromosome of each pair. Understand that only certain cells in a multicellular organism undergo meiosis.
12.11.16 Understand how random chromosome segregation explains the probability that a particular allele will be in a gamete.
12.11.17 Know why about half of an individual's DNA sequence comes from each parent. Understand that most of the cells in a human contain pairs of 22 different autosomes and one pair of sex chromosomes.
12.11.18 Understand that in humans there is a pair of chromosomes that determines sex: a female usually contains two X chromosomes and a male usually contains one X and one Y chromosome.
12.11.19 Understand how to predict possible combinations of alleles in a zygote from the genetic makeup of the parents for simple dominant/recessive traits.
12.11.20 Understand that a multicellular organism develops from a single zygote, and its phenotype (i.e. its outward appearance) depends on its genotype (i.e. its genetic makeup), which is established at fertilization.
12.11.21 Understand that, in all living things, DNA (deoxyribonucleic acid) carries the instructions for specifying the characteristics of each organism. Understand that DNA is a large polymer formed from four subunits: A, G, C, and T (adenine, guanine, cytosine, thymine, a 5-carbon sugar and a phosphate). The chemical and structural properties of DNA explain how the genetic information that underlies heredity is both encoded in genes (as a string of molecular letters) and replicated (by a templating mechanism). Know that each DNA molecule in a cell is a single chromosome.
12.11.22 Understand that a gene is a set of instructions in the DNA sequence of each organism that specifies the sequence of amino acids in polypeptides characteristic of that organism.
12.11.23 Understand the general steps by which ribosomes synthesize proteins, using information from mRNA and from amino acids delivered by tRNA.
12.11.24 Understand that specialization of cells in multicellular organisms is usually due to different patterns of gene expression rather than to differences of the genes themselves.
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